## Dr Dumitru Trucu

## Publications and Selected Scientific Presentations

##### List of Publications:

- Dumitru Trucu, Ping Lin, Mark A. J. Chaplain and Alastair Thompson (2015), "Exploring the multiscale interface dynamics of the cancer cells invasion of tissue",
**to be submitted soon in***Mathematical Models and Methods in Applied Sciences (M3AS) Journal* - Lu Peng, Dumitru Trucu, Ping Lin, Alastair Thompson, and Mark A. J. Chaplain (2015) "A multiscale mathematical model of tumour invasive growth"
- Yangjin Kim, Hyunji Kang, Gibin Powathil, Hyeongi Kim, Dumitru Trucu, Wanho Lee, Sean Lawler and Mark A. J. Chaplain (2015), "The role of miR-451-AMPK-mTOR in regulation of cell proliferation and inltration",
*Journal of the Royal Society Interface*(**submitted**) - Pia Domschke, Dumitru Trucu, Alf Gerisch and Mark A. J. Chaplain (2015), "Modelling surface-bound reactions through structured population models",
*Journal of Mathematical Biology*(33pp) (**submitted**) - Yangjin Kim, Gibin Powathil, Hyunji Kang, Dumitru Trucu, Hyeongi Kim, Sean Lawler and Mark A. J. Chaplain (2014), "Strategies of eradicating glioma cells: A multi-scale mathematical model with miR-451-AMPK-mTOR control",
*PLoS One*(31pp) ()__accepted__ - Pia Domschke, Dumitru Trucu, Alf Gerisch and Mark A. J. Chaplain (2014), "Mathematical modelling of cancer invasion: Implications of cell adhesion variability for tumour infiltrative growth patterns",
*Journal of Theoretical Biology*,**Vol 361**, pp. 41-60 - Dumitru Trucu and Mark A. J. Chaplain (2014), "Multiscale Analysis and Modelling for Cancer Growth and Development",
*Managing Complexity, Reducing Perplexity*, Springer Proceedings in Mathematics & Statistics*(Springer)*,**Vol 67**(eds. M. Delitala and G. Ajmone Marsan), pp.45-53, doi: 10.1007/978-3-319-03759-2_5 - Dumitru Trucu, Ping Lin, Mark A. J. Chaplain and Yangfan Wang (2013), "A Multiscale Moving Boundary Model Arising in Cancer Invasion",
*Multiscale Modeling and Simulations: A SIAM Interdisciplinary Journal*,**Vol 11**, No 1, pp. 309-335 - Dumitru Trucu, Mark A. J. Chaplain and Anna Marciniak-Czochra (2012), "Three-scale convergence for processes in heterogeneous media",
*Applicable Analysis: An International Journal (Taylor and Francis)*,**Vol 91**, No 7, pp. 1351-1373 - Dumitru Trucu, Derek B. Ingham and Daniel Lesnic (2011), "Reconstruction of the Space- and Time-Dependent Blood Perfusion Coefficient in Bio-Heat Transfer",
*Heat Transfer Engineering (Taylor and Francis)*,**Vol 32**, pp. 800-810, doi: 10.1080/01457632.2011.525430 - Dumitru Trucu, Derek B. Ingham and Daniel Lesnic (2010), "Inverse Temperature-Dependent Perfusion Coefficient Reconstruction",
*International Journal of Non- Linear Mechanics (Elsevier)*,**Vol 45**, pp. 542-549 - Dumitru Trucu, Derek B. Ingham and Daniel Lesnic (2010), "Space- dependent perfusion coefficient identification in the transient bio-heat equation",
*Journal of Engineering Mathematics (Springer)*,**Vol 67**, No 4, pp. 307-315 - Daniel Lesnic and Dumitru Trucu (2010), "The identification of blood perfusion coefficient in bio-heat transfer",
*Inverse Problems, Design and Optimization (IPDO- 2010)*, (eds. Z. E. Da Silva, H. R. B. Orlande, M. J. Colaco and G.S. Dulikravich) pp. 277-284**(peer reviewed)** - Dumitru Trucu, Derek B. Ingham and Daniel Lesnic (2009), "An inverse coefficient identification problem for the bio-heat equation",
*Inverse Problems in Science and Engineering, (Taylor and Francis)*,**Vol 17**, No 1, pp. 65-83 - Dumitru Trucu, Derek B. Ingham and Daniel Lesnic (2008), "Inverse Space-Dependent Perfusion Coefficient Identification",
*Journal of Physics: Conference Series (Institute of Physics)***Vol 135**, 012098 (8pp), doi: 10.1088/1742-6596/135/1/012098 - Dumitru Trucu, Derek B. Ingham and Daniel Lesnic (2008), "Inverse Time-Dependent Perfusion Coefficient Identification",
*Journal of Physics: Conference Series (Institute of Physics)*,**Vol 124**, 012050 (28pp), doi:10.1088/1742-6596/124/1/012050 - Dumitru Trucu, Derek B. Ingham and Daniel Lesnic (2007), "Direct boundary element method for the transient bio-heat transfer
equation",
*Advances in Boundary Integral Methods*, Proceedings of the Sixth UK Conference on Boundary Integral Methods, (ed. J.Trevelyan), Durham University, Ch.**24**, pp. 223-232**(peer reviewed)** - Dumitru Trucu, Derek B. Ingham and Daniel Lesnic (2007), "The inverse coefficient identification problem in bio-heat transient flow
equation",
*Inverse Problems, Design and Optimization (IPDO-2007), (eds. G.S. Dulikravich, M.J. Colaco, H.R.B. Orlande and M. Tanaka)*, Vol.**I**, pp. 214-221**(peer reviewed)**

*Bulletin of Mathematical Biology*(38pp) (

**submitted**)

##### Presentations Given in Conferences and Scientific Seminars:

–*"Novel multiscale computational modelling and analysis for cancer invasion: exploring the role of matrix-degrading enzymes in tumour progression"***Invited Plenary Speaker Talk**– given in the international conference on Perspectives in Environmental and System Biology, 13-15 April 2015, Universite Joseph Fourier, Grenoble, France– Invited Scientific Seminar Lecture - given in the Maths and Applications Sussex Seminar (MASS), Department of Mathematics, University of Sussex, 05 February 2015, Falmer Campus, Brighton, UK*"New horizons in multiscale modelling and analysis: the novel concept of three-scale convergence"*– Invited Scientific Seminar Lecture - given in the Biological Physics and System Biology Seminar Series, Universite de Montpellier, 15 January 2015, Montpellier, France*"Multiscale computational modelling of cancer growth and spread: a novel three-scale mathematical approach "*– Invited Scientific Seminar Lecture - given in the AG Mathematics with Applications to Biology and Medicine Seminar Series, Biomathematics Group, Department of Mathematics,, Technische Universität Kaiserslautern, 12 December 2014, Kaiserslautern, Germany*"Multiscale computational modelling of cancer invasion: a novel three-scale mathematical approach "*– Invited Scientific Seminar Lecture - given in the Numerical Analysis Seminar, Numerical Analysis and Scientific Computing Group, Department of Mathematics,, Technische Universität Darmstadt, 04 December 2014, Darmstadt, Germany*"Novel perspectives in multiscale modelling and analysis: the novel concept of three-scale convergence"*– Invited Scientific Seminar Lecture - given in the Numerical Analysis Seminar , Section of Mathematics, University of Geneva, 25 November 2014, Geneva, Switzerland*"New perspectives in multiscale analysis: the novel concept of three-scale convergence"*–*"Multiscale computational modelling and analysis for cancer invasion: exploring the role of matrix-degrading enzymes and adhesion in tumour progression"***Invited Plenary Speaker Talk**– given in the International Conference on Mathematics for the Natural and Life Sciences, 09-11 November 2014, University of Tlemcen, Tlemcen, Algeria– Series of Four Plenary Lectures – given in the ESMTB CIME-CIRM Summer School on "Mathematical Models and Methods for Living Systems", Levico Terme, 01-06 September 2014, Trento, Italy*"Multiscale computational modelling and analysis of cancer invasion"*– Invited Talk – given in the Special Session 62: “Mathematical Models of Cell Migration, Tumor Growth and Cancer Dynamics”, within The 10th AIMS Conference on Dynamical Systems, Differential Equations and Applications, Chalmers Conference Centre, 07-11 July 2014, Instituto de Ciencias Matemáticas (ICMAT) and Universidad Autónoma de Madrid (UAM), Madrid, Spain*"Multiscale modeling and analysis for cancer development: exploring the role of matrix-degrading enzymes and adhesion in invasion"*– Contributed Presentation – given in the 9th European Conference on Mathematical and Theoretical Biology –ECMTB 2014, Chalmers Conference Centre, 15-19 June 2014, Chalmers University, Gothenburg, Sweden– Poster Presentation – given in the Porous Media Processes and Mathematics (PMPM) Research Network, ICMS Edinburgh, 08-10 January 2014, Edinburgh, Scotland, UK*"Multiscale computational modelling of breast cancer invasion: Towards a predictive patient-based tool"*–*"Three-scale convergence: a novel concept in multiscale analysis"***Invited Plenary Speaker Talk**– given in the Infinite Dimensional Dynamical Systems in the Applied Sciences, University of Stirling, 13-14 December 2013, Stirling, Scotland, UK– Invited Scientific Seminar Lecture – given in the cfAED Cluster of Excellence Seminar Series, Technical University of Dreseden, 25 June 2013, Dresden, Germany*"Multiscale modeling and analysis for cancer invasion"*-*"Multiscale modeling and analysis for cancer growth and spread"***Invited Plenary Speaker Talk**- given in the "Workshop on Mathematical Models and Methods for Multiscale and Heterogeneous Structures", 20 June 2013, University of Heidelberg, Heidelberg, Germany- Contributed Presentation - given in the "SMB 2013: The Society for Mathematical Biology Annual Meeting and Conference", 10 - 13 June 2013, Arizona State University , Tempe, Arizona, USA*"Multiscale computational modeling and analysis of cancer growth and spread"*-*"Multiscale modeling and analysis for cancer invasion"***Invited Plenary Speaker Talk**- given in the "Scottish Partial Differential Equations Colloquium", ICMS Edinburgh, 17 May 2013, Edinburgh, Scotland, UK- Contributed Presentation – given in the "British Applied Mathematics Colloquium 2013", 09-12 April 2013, University of Leeds, Leeds, England, UK*"Multiscale computational modeling and analysis of cancer invasion"*- Poster Presentation - given in the "Second Systems Biology Symposium (SBS2)", 29th March 2013, University of Aberdeen, Aberdeen, Scotland, UK– Invited Scientific Seminar Lecture - given in the Inverse Problems Seminar, Department of Mathematics,, Colorado State University, 13 December 2012, Fort Collins, CO, USA*"Multiscale modeling, analysis, and computational simulations of cancer invasion"*- Poster Presentation - given in*"Multiscale computational modeling of breast cancer invasion: Towards a predictive patient-based tool"**The 2012 CTRC-AACR San Antonio Breast Cancer Symposium*, 04 – 08 December 2012, Henry B. Gonzalez Convention Center, San Antonio, Texas, USA[Abstract] - Invited Scientific Seminar Lecture - given in the*"Multiscale analysis and modelling for cancer growth and development"**Computational Mathematics and Mathematical Biology Seminar*,*Department of Mathematics*, Heriot-Watt University, 23 November 2011, Edinburgh, UK- Contributed Presentation - given in the*"Three-scale convergence for processes in heterogeneous media"**7th International Congress on Industrial and Applied Mathematics*- ICIAM 2011, 18 – 22 July 2011, Vancouver Convention Centre, Vancouver, BC, Canada-*"Multiscale modelling of cancer growth and development"***Invited Plenary Speaker Talk**- given in the Interdisciplinary International*Kepler Workshop on Complex Living Systems: "Managing complexity, reducing perplexity"*, 16-20 May 2011, University of Heidelberg, Heidelberg, Germany– Invited Scientific Seminar Lecture - given in the Biocomplexity Institute Seminar, Indiana University, 28 April 2011, Bloomington, IN, USA*"Towards a new type of analysis for multiscale processes in complex biomedical systems"*- Contributed Presentation - given in the*"Three-scale convergence for processes in heterogeneous media"**"British Applied Mathematics Colloquium 2011 (incorporating the 53rd British Theoretical Mechanics Colloquium)"*, 11-13 April 2011, University of Birmingham, Birmingham, UK– Invited Scientific Seminar Lecture - given in the*"Multiscale convergence for processes in heterogeneous media"**School of Computing and Mathematical Sciences Seminar Series*, University of Greenwich, 02 December 2010, London, UK- Poster Presentation - given in the London Mathematical Society - EPSRC Durham Symposium*"Inverse Perfusion Coefficient Identification in Bio-Heat Transient Flow"**"Numerical Analysis of Multiscale Problems"*, 05-15 July 2010, Department of Mathematical Sciences, University of Durham, Durham, UK- Invited Scientific Seminar Lecture - given in the Main Seminar of the Applied Analysis Group:*"Perfusion Coefficient Reconstruction in Bio-Heat Transient Flow"**"Angewandte Analysis"*, 04 May 2010, Applied Analysis Group, University of Heidelberg, Heidelberg, Germany- Contributed Presentation - given in the Maths2010 "*"Perfusion Coefficient Reconstruction in Bio-Heat Transient Flow"**British Mathematical Colloquium and British Applied Mathematics Colloquium*", 06-09 April 2010, ICMS, University of Edinburgh, Edinburgh, UK- Invited Scientific Seminar Lecture - given in the University of Dundee Applied Mathematics Seminars, 01 December 2009, Division of Mathematics, University of Dundee, Dundee, UK*"Inverse problems for the bio-heat equation"*- Contributed Presentation - given in Mathematics Applied to the Life Sciences*"Temperature-Dependent Perfusion Coefficient Reconstruction"**"Mathematical Biology Ph.D. Meeting"*, 02 October 2009, Wolfson Medical School Building, University of Glasgow, Glasgow, UK[Abstract] - Poster Presentation - given in the AIP 2009, Second International Congress of IPIA:*"Inverse Perfusion Coefficient Identification in Bio-Heat Transient Flow"**"Conference on Applied Inverse Problems 2009*", 20-24 July 2009, University of Vienna, Vienna, Austria[Abstract] - Contributed Presentation - given in the "*"Temperature-Dependent Perfusion Coefficient Reconstruction"**British Applied Mathematics Colloquium 2009 (incorporating the 51st British Theoretical Mechanics Colloquium)*", 07-09 April 2009, The University of Nottingham, UK- Contributed Presentation - given in the "Inverse Problems and Applications", 16 December 2008, Department of Science and Technology (ITN), Campus Norrköping, Linköping University, Sweden.*"Inverse Perfusion Coefficient Problems in the Transient Bio-Heat Equation"*- Contributed Presentation - given in the " 6th International Conference on Inverse Problems in Engineering: Theory and Practice", 15-19 June 2008, Dourdan (Paris), France.*"Inverse Space-Dependent Perfusion coefficient identification in the Transient Bio-Heat Equation"*- Contributed Presentation - given in the "6th UK Conference on Boundary Integral Methods ", University of Durham, 17-18 September 2007, Durham, United Kingdom.*"Direct Boundary Element Method for the Bio-Heat Transient Flow Equation"*[Abstract] - Contributed Presentation - given in the " AIP 2007 First International Congress of IPIA,*"The Inverse Time-dependent Coefficient Identification Problem in Bio-Heat Transient Flow Equation"**"Conference on Applied Inverse Problems 2007: Theoretical and Computational Aspects"*, 25-29 June 2007, University of British Columbia Campus Vancouver, Canada[Abstract] - Contributed Presentation - given in the*"The Inverse Coefficient Identification Problem in Bio-Heat Transient Flow Equation"**"Inverse Problems, Design and Optimization Symposium"*, IPDO2007, 16-18 April 2007, Miami, FL, USA.- Invited Scientific Seminar Lecture - given in the Colorado State University Applied Mathematics Seminar, 27 February 2003, Department of Mathematics, Colorado State University, Fort Collins, CO, USA*"Duality Theorems for Convex Processes"*