Mathematical Biology at Dundee has a long and distinguished
history. In 1884 Professor D'Arcy Wentworth Thompson was appointed
as Professor of Biology and remained in Dundee for 33 years until
1917 when he moved to St. Andrews. D'Arcy Thompson, author of "Growth
and Form", was perhaps the first mathematical biologist. A conference to
mark the 50th anniversary of his death in 1998 is being held in Dundee
Moving to the present day, the Mathematical Biology and Applied Analysis
group at the Department of Mathematics, Dundee University, is
directed by Dr. MAJ Chaplain and Dr. PD Smith. The research in this group
focuses on the spatio-temporal dynamics of nonlinear, heterogeneous
biological systems. This is an exciting area of modern applied
mathematics offering many fascinating and challenging problems both
mathematically and biologically. Work is currently being undertaken in
modelling problems in developmental biology (cell movement via
chemotaxis, haptotaxis, nonlinear diffusion), morphogenesis, plant
cell wall growth and expansion, the theory of pain, solid tumour
growth and development, angiogenesis (formation of capillary
networks), tumour invasion and metastasis, host-parasitoid
interactions, wound healing and transport in soil environments. The
models normally consist of nonlinear systems of difference equations,
ordinary differential equations or partial differential equations. A
blend of analytical (stability analyses, bifurcation theory, nonlinear
analysis) and numerical techniques (finite difference/element
approximations) is used in addition to mathematical modelling skills.
Close collaboration with biological colleagues is pursued and encouraged
and links are already set up with the departments of Anatomy and
Physiology (cell movement, Dyctiostelium discoideum), Biology (ecology,
predator-prey models, host-parasitoid models, plant cell growth and
morphogenesis), Pathology (cancer modelling), Biochemistry (p53
tumour-suppressor gene modelling) and Dental Surgery & Periodontolgy
(endothelial cell movement, fibroblast movement, angiogenesis). The
Mathematics Department also runs an MSc course in Mathematical Biology.
The Centre for Nonlinear Systems in Biology, established in 1991, is
active in promoting joint research between the Mathematics Department, the
Scottish Crop Research Institute (SCRI) and Biomathematics and Statistics
Scotland (BioSS). The aims of the Centre are to pursue interdisciplinary
research programmes involving novel mathematical and statistical
techniques in support of biological research.
Mathematical Biology at SCRI is undertaken in the Unit of Integrative
Bioscience, lead by Dr JW Crawford, heading a team comprising Drs IM
Young, G. Squire, B. Marshall, K. Ritz, J. Liu, B. Griffiths.
Mathematical modelling is currently being done in areas such as nonlinear
diffusion and transport processes in soil and other porous media,
complex biochemical systems, geneflow in agricultural and semi-natural
systems: competition, invasions and succession, role of variation in
functional trait in the stability of species-rich vegetation, quantifying
the relation between physical structure and biological function,
application of fractal geometry to soil structure and its relation to
transport processes, fungal morphogenesis in nutritionally heterogeneous
environments, origin and characterisation of stability in nonlinear
systems subject to noise.
Mathematical Biology research at BioSS is led by Dr. J. McNicol and work
is currently being undertaken in the areas of image analysis,
environmental modelling, epidemiology, molecular biology and genetics,
crop systems, food and nutrition.
Further information on mathematical biology research at Dundee is
available from the respective web sites:
http://www.mcs.dundee.ac.uk:8080/
http://www.scri.sari.ac.uk:80/
http://www.bioss.sari.ac.uk:80/
or contact
Dr. Mark A.J. Chaplain
Department of Mathematics and Computer Science
University of Dundee
Dundee DD1 4HN
Scotland
e-mail: chaplain@mcs.dundee.ac.uk
home page: http://www.mcs.dundee.ac.uk:8080/~chaplain/
tel: +44 1382 345369
FAX: +44 1382 345516